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Effect of nucleolin deletion mutants on c-MYC G-quadruplex thermal stability.
| Nucleolin Deletion Mutants | Tm (°C) | −ΔTm in comparison to Nuc-1,2,3,4-RGG |
|---|---|---|
| Nuc-1,2,3,4-RGG | 59 | – |
| Nuc-1,2,3,4 | 43 | 16 |
| Nuc-1,2,3 | 41 | 18 |
| Nuc-1,2 | 43 | 16 |
| Nuc-2,3,4-RGG | 51 | 8 |
| Nuc-3,4-RGG | 58 | 1 |
| Nuc-4-RGG | 43 | 16 |
| Nuc-RGG | 55 | 4 |
| Nuc-1,2-RGG | 52 | 7 |
| Nuc-2,3-RGG | 43 | 16 |
