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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Proteins. 2010 Oct 11;78(16):3473–3487. doi: 10.1002/prot.22853

Figure 7.

Figure 7

Model of the binding of MRS2485 in the central region of the pore. (A) Side view of portion or the pore formed by residues 11–21 with one MRS2485 molecule (space-filled colored by element) bound. Subunits nearest the viewer have been removed to reveal the lining of the central pore. (B) Same as (A) but with six bound MRS2485 drugs. These are related by 3-fold symmetry about the axis of the pore and 2-fold symmetry about the central plain. (C) Top view of the C-termini ends (residues 11–14) of S1 segments with three bound MRS2485 drugs.

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