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. Author manuscript; available in PMC: 2011 Nov 16.
Published in final edited form as: Biochemistry. 2010 Oct 22;49(45):9874–9881. doi: 10.1021/bi101449f

Figure 1.

Figure 1

Structure of wt human PrPC. The starting structure used for MD simulations, residues 90-230. Secondary structure elements in the C-terminal globular domain are labeled. The three residues involved in the point mutations studied in this work are shown as sticks.