Table 1.
Change in cartilage morphology (in the right knee) over 1 year for the total subcohort, and for women and men, respectively
| All (n = 156) | Women (n = 79) | Men (n = 77) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MC% | SRM | p Value | MC% | SRM | p Value | MC% | SRM | p Value | ||
| MT | VC | −0.42 | −0.12 | 0.13 | −0.40 | −0.13 | 0.25 | −0.44 | −0.12 | 0.28 |
| ThCtAB | −0.52 | −0.16 | 0.04* | −0.46 | −0.14 | 0.22 | −0.58 | −0.18 | 0.11 | |
| ThCcAB | −0.34 | −0.12 | 0.14 | −0.23 | −0.08 | 0.47 | −0.44 | −0.15 | 0.19 | |
| cAB | −0.19 | −0.11 | 0.19 | −0.31 | −0.14 | 0.22 | −0.11 | −0.07 | 0.56 | |
| cMF | VC | −1.49 | −0.21 | 0.008* | −1.14 | −0.18 | 0.12 | −1.74 | −0.25 | 0.03* |
| ThCtAB | −1.92 | −0.30 | <0.001* | −1.69 | −0.26 | 0.02* | −2.12 | −0.34 | 0.004* | |
| ThCcAB | −1.46 | −0.26 | 0.002* | −1.34 | −0.23 | 0.047* | −1.56 | −0.28 | 0.02* | |
| cAB | −0.47 | −0.12 | 0.14 | −0.20 | −0.06 | 0.61 | −0.69 | −0.17 | 0.15 | |
| MFTC | VC | −0.79 | −0.22 | 0.007* | −0.66 | −0.19 | 0.10 | −0.88 | −0.25 | 0.03* |
| ThCtAB | −1.23 | −0.31 | <0.001* | −1.08 | −0.26 | 0.03* | −1.37 | −0.37 | 0.002* | |
| LT | VC | −0.55 | −0.17 | 0.03* | −0.55 | −0.14 | 0.21 | −0.55 | −0.20 | 0.08 |
| ThCtAB | −0.68 | −0.23 | 0.005* | −0.76 | −0.21 | 0.07 | −0.60 | −0.27 | 0.02* | |
| ThCcAB | −0.60 | −0.21 | 0.009* | −0.68 | −0.19 | 0.09 | −0.52 | −0.24 | 0.04* | |
| cAB | 0.03 | 0.02 | 0.78 | 0.15 | 0.11 | 0.32 | −0.06 | −0.05 | 0.67 | |
| cLF | VC | 0.02 | 0.01 | 0.95 | 0.67 | 0.13 | 0.27 | −0.42 | −0.11 | 0.33 |
| ThCtAB | 0.09 | 0.02 | 0.77 | 0.60 | 0.13 | 0.26 | −0.35 | −0.11 | 0.35 | |
| ThCcAB | 0.13 | 0.03 | 0.67 | 0.70 | 0.15 | 0.18 | −0.37 | −0.12 | 0.30 | |
| cAB | 0.01 | 0.00 | 0.95 | −0.06 | −0.04 | 0.75 | 0.06 | 0.03 | 0.77 | |
| LFTC | VC | −0.33 | −0.12 | 0.14 | −0.09 | −0.02 | 0.83 | −0.50 | −0.21 | 0.07 |
| ThCtAB | −0.30 | −0.11 | 0.17 | −0.10 | −0.03 | 0.80 | −0.48 | −0.23 | 0.046* | |
cAB, cartilage-covered bone area; cLF, weight-bearing lateral femoral condyle; cMF, weight-bearing medial femoral condyle; LFTC, lateral femoro-tibial compartment; LT, lateral tibia; MC%, mean change (in %); MFTC, medial femoro-tibial compartment; MT, medial tibia; SRM, standardised response mean (mean change/SD of change); ThCcAB, thickness of the cartilage over the entire cAB; ThCtAB, thickness of the cartilage over the entire subchondral bone area; VC, volume of cartilage.
p Values <0.05 for paired t test between baseline and 1 year, without correcting for multiple testing, showing that the rate of loss was significantly different from zero.