Table 5.

Change in cartilage thickness over the entire subchondral bone area (ThCtAB) over 1 year for participants with radiographic OA (ROA: K-L grade ≥2) and frequent symptoms (FS), with ROA and obesity, with K-L grade 3 and obesity and with K-L grade 3, obesity and FS

	ROA+FS (n = 87)			ROA+obesity (n = 57)			K-L 3+obesity (n = 29)			K-L 3+obesity+FS (n = 23)
	MC%	SRM	p Value	MC%	SRM	p Value	MC%	SRM	p Value	MC%	SRM	p Value
MT	−0.52	−0.16	0.04*	−0.95	−0.24	0.08*	−0.81	−0.17	0.37	−0.35	−0.07	0.74
cMF	−1.92	−0.30	<0.001*	−3.98	−0.46	<0.001*	−4.38	−0.48	0.02*	−5.06	−0.52	0.02*
MFTC	−1.23	−0.31	<0.001*	−2.45	−0.45	0.001*	−2.48	−0.42	0.03*	−2.55	−0.40	0.07
LT	−0.68	−0.23	0.005*	−1.11	−0.39	0.005*	−1.27	−0.49	0.01*	−1.40	−0.51	0.02*
cLF	0.09	0.02	0.77	0.06	0.01	0.92	0.46	0.10	0.61	0.31	0.06	0.77
LFTC	−0.30	−0.11	0.17	−0.52	−0.18	0.17	−0.39	−0.13	0.50	−0.53	−0.16	0.44

^*p Values <0.05 for paired t test between baseline and 1 year, without correcting for multiple testing, showing that the rate of loss was significantly different from zero.

For abbreviations see the footnotes of table 1.