Table VI.
In vitro Aerosol Deposition Data of Spray Dried Formulations
Formulations | Emitted dose (%) | Fine particle fraction (%) | Mean median aerodynamic diameter (μm) | GSD |
---|---|---|---|---|
SLDPIH | 87 ± 2 | 75.6 ± 1.6 | 2.2 ± 0.1 | 2.3 ± 0.1 |
SLDPIS | 67 ± 4 | 55.9 ± 1.7 | 2.8 ± 0.1 | 2.9 ± 0.2 |
SLDPIL | 78 ± 2 | 62.8 ± 2.8 | 2.5 ± 0.2 | 2.6 ± 0.2 |
Mean ± SD, n = 6
SLDPIH: spray dried liposomal dry powder inhaler with hydrolyzed gelatin, SLDPIS: spray dried liposomal dry powder inhaler with sucrose, SLDPIL: spray dried liposomal dry powder inhaler with lactose