Table III.
Physical Characteristics of Reservoir and Rate Controlling Films
Parameters tested | Sodium Alginate Reservoir Films | Rate Controlling Eudragit Films | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
A | B | C | D | E | 1 | 2 | 3 | 4 | 5 | |
Percentage elongation at break | 10 ± 1.52 | 13 ± 0.57 | 14 ± 1.15 | 18 ± 0.53 | 14 ± 2.5 | 18 ± 1.2 | 18 ± 2.0 | 20 ± 1.0 | 25 ± 0.5 | 19 ± 1.5 |
Drug Content (mg) per reservoir | 1.85 ± 0.55 | 1.90 ± 0.50 | 1.95 ± 0.32 | 2.01 ± 0.02 | 2.10 ± 0.22 | – | – | – | – | – |
Thickness(μm) | 150 ± 1.0 | 150 ± 1.0 | 151 ± 1.3 | 155 ± 0.5 | 156 ± 0.5 | 48 ± 2.0 | 47 ± 1.5 | 50 ± 1.0 | 50 ± 1.5 | 50 ± 2 |
Results are mean of five observations ± standard deviation; values are rounded up to nearest value