Table 3.
Evaluation Parameters of Different Formulations
| Batch Code | Wt. of 20 Tabs. (mg) | Friability (%) | Disint. Time (s) | Diameter (mm) | Thickness (mm) | Hardness (kg.) | Diss. Test (%) | Assay 247 nm (%) |
|---|---|---|---|---|---|---|---|---|
| F1 | 135.08 ± 0.223 | 0.071 | 25 | 6.495 ± 0.015 | 4.872 ± 0.061 | 6.990 ± 0.098 | 94.08 | 97.56 |
| F2 | 132.42 ± 0.912 | 0.156 | 22 | 6.495 ± 0.015 | 4.897 ± 0.041 | 5.959 ± 0.073 | 92.56 | 96.95 |
| F3 | 137.07 ± 0.744 | 0.150 | 28 | 6.492 ± 0.018 | 4.910 ± 0.030 | 6.977 ± 0.119 | 95.59 | 95.27 |
| F4 | 140.23 ± 0.668 | 0.142 | 18 | 6.492 ± 0.018 | 4.920 ± 0.034 | 8.027 ± 0.175 | 94.84 | 96.64 |
| F5 | 137.40 ± 0.587 | 0.071 | 21 | 6.492 ± 0.018 | 4.905 ± 0.042 | 6.525 ± 0.277 | 93.32 | 97.40 |
| F6 | 132.42 ± 0.315 | 0.155 | 36 | 6.495 ± 0.015 | 4.900 ± 0.039 | 7.230 ± 0.249 | 96.35 | 97.86 |
| F7 | 130.42 ± 0.706 | 0.251 | 11 | 6.492 ± 0.018 | 4.897 ± 0.044 | 6.998 ± 0.232 | 99.39 | 99.69 |
| F8 | 120.42 ± 0.758 | 0.080 | 11 | 6.495 ± 0.015 | 4.837 ± 0.042 | 7.867 ± 0.251 | 96.96 | 98.32 |
| F9 | 150.29 ± 0.906 | 0.208 | 10 | 6.495 ± 0.015 | 5.707 ± 0.037 | 5.083 ± 0.308 | 95.90 | 97.10 |
| Limits | ±7.5% | <than 1% | <then 15 min | ±5% | ±5% | 6–10 | ≥75 | 92.5–107.5 |