Table III.
Properties of Core Tablets, and Coated Tablets of the Optimized Formulation (Batch-III/80/CT3)
| Parameters | Value ± SD |
|---|---|
| Tablet weight (mg, n = 10) | |
| Core tablet | 500 ± 5.58 |
| SPM coated tablet | 514 ± 4.48 |
| Compression coated tablet | 764 ± 4.54 |
| Thickness (mm, n = 10) | |
| Core tablet | 5.75 ± 0.04 |
| SPM coated tablet | 5.84 ± 0.02 |
| Compression coated tablet | 6.74 ± 0.02 |
| Diameter (mm, n = 10) | |
| Core tablet | 10.01 ± 0.11 |
| SPM coated tablet | 10.09 ± 0.08 |
| Compression coated tablet | 10.99 ± 0.12 |
| Hardness (kg/cm2) | |
| Core tablet | 6.12 ± 1.12 |
| SPM coated tablet | 10.24 ± 1.48 |
| Friability (%) | |
| Core tablet | 0.096 |
| Compression coated tablet | 0.089 |
| Content uniformity (%, n = 10) | 102.26 ± 2.24 |
| Thickness of compression coat (μm, n = 10) | 900 ± 0.04 |
SPM Semipermeable membrane