Table I.
Solubilization Efficiencies of NMP, EtOH and PG
| Drug | Log K ow | Log S int (μg/ml) | S 0.2/S int | ||
|---|---|---|---|---|---|
| NMP | EtOH | PG | |||
| Phenobarbital | 1.5 | 2.99 | 6.2 | 2.1 | 1.5 |
| Carbendazim | 1.5 | 0.37 | 31.7 | 6.9 | 5.9 |
| PPA | 1.9 | 3.47 | 7.4 | 4.4 | 4.1 |
| Griseofulvin | 2.2 | 0.91 | 25.1 | 9.7 | 4.4 |
| Phenytoin | 2.5 | 1.03 | 29.1 | 6.5 | 4.5 |
| PG-300995 | 2.6 | 1.59 | 15.3 | 7.3 | 3.3 |
| Ketoprofen | 3.1 | 1.89 | 47.4 | 6.1 | 3.2 |
| Estrone | 3.1 | −0.20 | 47.0 | 13.6 | 6.8 |
| Testosterone | 3.3 | 1.34 | 14.9 | 8.6 | 4.2 |
| Ibuprofen | 3.5 | 1.48 | 20.6 | 10.8 | 6.4 |
| XK-469 | 3.9 | −0.64 | 50.2 | 9.1 | 4.5 |
| Amiodarone | 5.9 | 0.18 | 389.1 | 67.5 | 16.9 |
| BPU | 6.2 | −1.55 | 795.8 | 102.5 | 145.0 |