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. 2008 May 6;9(2):577–582. doi: 10.1208/s12249-008-9092-2

Table III.

In-vitro Dissolution Profile of Propranolol HCl from the Formulations Containing HPMC K15 or Kollidon® SR in pH 6.8 Phosphate Buffer

Sr. No. Mean cumulative percent ± S.D drug released
Time (h) PrH 1 PrH 2 PrH 3 PrH 4 PrK1 PrK2 PrK3 PrK4
1. 1 33.31 ± 0.98 13.36 ± 1.17 13.788 ± 1.22 11.56 ± 0.93 32.23 ± 1.21 13.23 ± 1.34 9.22 ± 1.23 8.22 ± 1.1
2. 2 62.06 ± 0.91 25.87 ± 0.39 27.894 ± 1.54 18.74 ± 1.61 58.76 ± 0.76 24.26 ± 1.56 18.24 ± 1.65 16.65 ± 2.1
3. 3 87.32 ± 1.44 36.06 ± 1.30 42.373 ± 0.98 28.24 ± 0.69 81.34 ± 1.22 35.34 ± 1.67 27.31 ± 1.87 23.34 ± 1.43
4. 4 98.18 ± 0.52 53.39 ± 0.57 52.755 ± 0.78 39.36 ± 0.76 97.98 ± 1.21 51.25 ± 1.98 35.32 ± 1.90 30.56 ± 1.34
5. 5 67.14 ± 0.77 62.260 ± 0.87 50.99 ± 0.69 65.28 ± 2.10 44.31 ± 1.98 36.29 ± 1.87
6. 6 73.86 ± 0.62 71.189 ± 1.34 59.18 ± 0.85 76.23 ± 1.67 52.38 ± 1.76 42.09 ± 1.98
7. 7 78.48 ± 0.09 75.973 ± 1.23 67.49 ± 0.72 87.45 ± 1.98 60.11 ± 0.89 47.59 ± 1.65
8. 8 84.60 ± 0.66 80.469 ± 1.43 73.43 ± 0.43 93.56 ± 1.87 68.22 ± 0.87 52.34 ± 1.56
9. 9 91.30 ± 0.64 83.311 ± 1.32 75.18 ± 0.96 97.45 ± 0.95 77.31 ± 0.89 57.98 ± 0.98
10. 10 95.84 ± 0.53 86.682 ± 1.12 79.45 ± 0.64 85.22 ± 0.67 62.6 ± 1.89
11 11 99.35 ± 0.31 89.669 ± 1.94 82.31 ± 0.68 91.22 ± 1.76 66.4 ± 1.95
12 12 91.215 ± 1.21 86.93 ± 0.81 97.23 ± 1.13 80.9 ± 1.76