Table IV.
Formulations | Zero-order Model | First-order Model | H-M Model | P-K Model | H-C Model | |||||
---|---|---|---|---|---|---|---|---|---|---|
R | K 1 | R | K 2 | R | K 3 | R | K 4 | R | K 5 | |
PrH3 | 0.9143 | 9.260 | 0.9987 | −0.202 | 0.9827 | 27.074 | 0.9812 | 16.701 | 0.9918 | −0.050 |
PrK3 | 0.9982 | 6.971 | 0.9742 | −0.117 | 0.9353 | 19.787 | 0.9976 | 6.338 | 0.9906 | −0.032 |
H-M Highuchi Matrix, P-K Peppas-Korsmeyer, H-C Hixon-Crowell, R correlation coefficient, K 1–K 5 constants of release kinetics