Skip to main content
. 2008 Mar 14;9(2):464–470. doi: 10.1208/s12249-008-9062-8

Table 3.

Effect of HPMC/EC Ratios on the Flux, Lag Time and Correlation Coefficient According to Zero Order and Higuchi’s Plots of Diltiazem HCl films

HPMC/EC ratio Flux‡ (μg/cm2 h) Lag timea (h) r 2 zero order plota r 2 Higuchi’s plota
10:0b 97 ± 33 0.75 0.980 ± 0.017 0.997 ± 0.005
8:2b 97 ± 9 0.73 0.985 ± 0.015 0.999 ± 0.011
6:4c 34 ± 5 2.31 0.960 ± 0.031 0.913 ± 0.045

aCalculated from time range of 3–12 h

b n = 8

c n = 5