Table IV.
Evaluation Parameter of MTH Tablet
| Batch | Weight (mg)a | Thickness (mm)a | Hardness (Kg/cm2)a | Friability (%)b | Disintegration time (s)a | Drug content (%)a |
|---|---|---|---|---|---|---|
| F1 | 101.0 (1.4) | 2.24 (0.05) | 4.50 (0.00) | 0.33 | 32.33 (5.53) | 99.9 (1.38) |
| F2 | 101.4 (1.2) | 2.30 (0.00) | 5.00 (0.49) | 0.19 | 52.16 (12.98) | 101.4 (0.87) |
| F3 | 99.2 (1.68) | 2.23 (0.04) | 4.00 (0.00) | 0.64 | 35.66 (4.58) | 101.2 (0.84) |
| F4 | 100.8 (1.2) | 2.17 (0.04) | 4.75 (0.35) | 0.29 | 191.50 (31.23) | 99.7 (2.08) |
| F5 | 99.9 (1.21) | 2.24 (0.05) | 4.10 (0.00) | 0.37 | 78.66 (22.34) | 101.3 (1.28) |
| F6 | 100.2 (1.0) | 2.19 (0.03) | 4.90 (0.14) | 0.58 | 105.80 (14.16) | 101.2 (0.84) |
| F7 | 100.1 (1.3) | 2.27 (0.04) | 3.90 (0.14) | 0.74 | 52.50 (12.27) | 102.2 (0.80) |
MTH Metoclopramide hydrochloride
aEach value represents as mean ± SD of three determinations
bEach value represents as singly