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Physical Characterization of Matrix Tablets of Carbamazepine
| Matrix formulation | CBZ content (%) | Weighta (mg) | Thicknessa (mm) | Hardnessa (kg/cm2) | Friabilityb (%) | Disintegrationa time (min) |
|---|---|---|---|---|---|---|
| Formula F | 102.34 ± 1.02 | 425.54 ± 1.35 | 3.0 ± 0.03 | 5.10 ± 0.32 | 0.65 ± 0.02 | 5.0 ± 0.02 |
| Formula L | 98.95 ± 0.98 | 270.3 ± 1.67 | 2.9 ± 0.06 | 6.3 ± 0.19 | 0.34 ± 0.03 | >360 min |
aData are the mean of ten determinations
bData are the mean of two determinations
