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Mathematical Modeling and Dissolution Parameters for Carbamazepine Release from Tegretol® CR and Formula F and L Matrix Tablets
| Matrix formulation | Regression coefficient (r) | Kinetic constant k, (h −n) | n | DE (%) | f 2 | MDT (h) |
|---|---|---|---|---|---|---|
| Formula F | 0.9799 | 33.32 | 0.654 | 68.5 | 61.3 | 1.99 |
| Formula L | 0.9929 | 34.90 | 0.637 | 65.4 | 56.0 | 2.10 |
| Tegretol® CR | 0.9989 | 44.46 | 0.433 | 71.3 | – | 1.91 |
