FIG. 3.

Specificity of rH1HA and rH5HA for mDC activation. rHAs were treated with proteinase K (PK) (2 mg/ml) at 37°C for 1 h prior to being added to mDC cultures. Intracellular TNF-α production was measured after holding for an additional 6 h. Values shown on the graphs indicate percentages of fluorescent TNF-α⁺ DCs cultured with the indicated stimuli (black line) compared to percentages for the control (gray line). Data represent average values from three independent experiments. PE, phycoerythrin.