FIG. 2.

Replication of the H7N7 NL/03 ca virus in ferrets. Shown are levels of replication of wt and ca viruses in ferrets following i.n. inoculation of 10⁷ TCID₅₀/ferret of the H7N7 NL/03 wt (•), H7N7 NL/03 ca (▪), AA wt (▴), and AA ca (⧫) viruses on 3 dpi. Virus titers in the indicated organs are expressed as log₁₀ TCID₅₀/g or log₁₀ EID₅₀/g of tissue. The solid line represents the mean for the group. The lower limit of detection is indicated by the dashed horizontal line. An asterisk indicates a statistically significant (P < 0.05) reduction in virus titers compared to the corresponding wt virus.