TABLE 4.

Replication of H7N7 NL/03 wt and H7N7 NL/03 ca viruses in African green monkeys

Virus	Day of necropsy	Animal	Virus titer in respiratory tissues (log10TCID50/g)			Virus titer in respiratory secretions (log10TCID50/ml)b
			Nasal turbinates	Trachea	Lungsa	Nasal/ pharyngeal swabs on day:		Nasal wash specimens on day:		Tracheal lavage fluid on day:
						2	4	2	4	2	4
H7N7 NL/03 wt	2	1	8.7	7.2	6.1 ± 1.77	3.2	ND	3.2	ND	3.2	ND
	2	2	8.2	7.7	6.5 ± 1.21	3.2	ND	3.2	ND	3.2	ND
	4	3	6.7	6.4	5.1 ± 1.21	3.2	3.2	1.5	<0.5c	ND	<0.5
	4	4	5.7	7	6.6 ± 0.41	3.1	6.7	5.2	1.5	ND	<0.5
H7N7 NL/03 ca	2	5	<1.5d	<1.5	<1.5	4.4	ND	3.2	ND	4.2	ND
	2	6	<1.5	<1.5	<1.5	3.9	ND	3.2	ND	<0.5	ND
	4	7	<1.5	<1.5	<1.5	5.2	3.4	3.2	<0.5	ND	4.0
	4	8	<1.5	<1.5	<1.5	4.2	4.2	2.4	4.0	ND	<0.5

^aMean titer of eight lung samples of individual AGMs ± SE.

^bND, not done.

^cDetection limit of virus in secretions.

^dDetection limit of virus in tissues.