FIG. 5.

Influenza virus infection induces proteins involved in several areas of the immune response. Proteins are color coded relative to the cluster to which they belong (Fig. 3). White proteins are proteins that were either not observed or not differentially expressed during infection. A large number of RNA binding proteins that function in recognizing viral nucleic acids and initiating a response were induced primarily during HPAI infection. Gray boxes indicate a functionally related class of proteins (to distinguish them from a subcellular localization compartment).