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. 2010 Sep 15;84(22):11802–11813. doi: 10.1128/JVI.01136-10

FIG. 1.

FIG. 1.

Weight loss and virus shedding in ferrets and mice inoculated with NL602-WT, NL602-D222E, or NL602-D222G. Data are shown for ferrets (A to C) and mice (D to F) inoculated with NL602-WT (▪), NL602-D222E (⧫), or NL602-D222G (▴). Body weights are depicted as the percentage of body weight at time of inoculation. Body weight is shown as average for six ferrets until 3 dpi and three ferrets from 4 to 7 dpi (A) or for five to six mice (D). Virus detection in throat swabs (B) and nose swabs (C) in ferrets are indicated for NL602-WT (▪), NL602-D222E (□), and NL602-D222G (░⃞). Geometric mean titers for positive samples are displayed, and error bars indicate the standard deviations. The lower limit of detection is indicated by the dotted line. The proportion of surviving mice is shown for each group (E). Virus titers in the lungs of inoculated mice (n = 3) were determined at 3 and 5 dpi, with the geometric mean titers and standard deviations indicated (F). Symbols and colors are consistent in panels A to F.