FIG. 4.

Global arrangement of Gag lattice in the particles. (A) Global lattice maps of in vitro-assembled Gag particles. The centers of each hexameric unit cell are marked with hexamers, which are colored according to cross correlation on a scale from low (red) to high (green). Higher cross-correlation values indicate that the subtomogram is more similar to the average structure. The cross-correlation range in the each map has been set between the minimum and the maximum cross-correlation value present in the map. Maps are shown in perspective, such that hexamers on the rear surface of the particle appear smaller and fainter. Two representative particles are shown for each genus. (B) Scatter plot showing the distribution of the angles between each hexamer and its neighbors (see Materials and Methods). The mean value for each particle is marked in red. For each construct, 12 particles have been analyzed.