. 2010 Sep 1;84(22):11916–11928. doi: 10.1128/JVI.01202-10

TABLE 2.

Comparison of amino acid differences between Chilean strains and other European isolates

Isolate	Comparison of amino acid differences^a
Isolate	PB2	PB1	NP	PA	Fusion	HE	NS1	NS2	Matrix	M2
ISAV752_09/others	V/M 146	F/Y 332	T/I 67	L/I 292^b	T/A 58^c	I/L 20	E/D 170^h	R/K 64ⁱ	IPS	A/V 19^J
	A/V 185			E/D 471^b	A/T 71	L/I 29^f				K/R 218
	P/S 229			R/K 531	G/N 252^d	N/S 154^g
					N/S 263^c	S/P 156
					Q/L 277^e	V/I 158
ISAV901_09/others	T/S 85	R/H 707^a	T/I 67	T/I 204	T/A 58^c	N/S 154^g	E/D 170^h	R/K 64ⁱ	IPS	R/W 116
			S/A 105	L/I 292^b	A/T 71	S/P 156
			S/A 558	A/T 328	G/N 252^d	D/N 164
				E/D 471^b	N/S 263^c	G/D 247
				R/K 531		A/K 338

Each value is indicated as first the amino acid difference and then the position number is given. Boldface, nonconservative amino acid substitution; IPS, identical protein sequences. Underlining indicates a novel mutation described for ISAV. Superscript letters: a, amino acid difference also found in virulent isolate ISAV1; b, amino acid difference also found in virulent isolates ISAV1, ISAV4, ISAV5, and low-virulence or avirulent isolates ISAV10, ISAV11, and SK779; c, amino acid difference also found in low-virulence or avirulent isolates ISAV8, ISAV10, ISAV11, and SK779; d, amino acid difference also found in low-virulence or avirulent isolates ISAV8 and SK779; e, amino acid difference also found in virulent isolate ISAV4 and avirulent isolate SK779/06; f, amino acid difference also found in virulent isolate ISAV8; g, amino acid difference also found in avirulent isolate SK779; h, amino acid difference also found in virulent isolates ISAV5, ISAV6, and ISAV7; i, amino acid difference also found in virulent isolates ISAV1, ISAV3, ISAV4, ISAV5, and low-virulence isolates ISAV8, ISAV10, and ISAV11; j, amino acid difference also found in virulent isolate ISAV5.