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Comparison of the GdnHCl1/2 values of PrPSc obtained in this study with those published previously
| Technique | GdnHCl1/2 value of PrPSc ina: |
Material analyzed | Reference | |||
|---|---|---|---|---|---|---|
| vCJD | sCJD MM1 | sCJD MM2A | sCJD VV2A | |||
| CDI | 1.678 | 2.344 | ND | 2.308 | Human brain | This study |
| PrPSc-specific capture | 1.850 | 2.450 | ND | ND | Human brain | 21 |
| CSA | ND | 2.760 | 1.420 | ND | Human brain | 7 |
| Detergent insolubility | ND | 2.950 | 1.460 | 2.690 | Bank vole brain | 40 |
ND = not determined.
