FIGURE 2.
Use of steroid pretreatment in a patient (LD 47) who received a homograft from his brother. Both were A blood type. Three days after operation, acute wound tenderness, hematuria, and anuria developed. Immediate relief followed the first dose (150 r) of transplant irradiation. Restoration of function was so rapid that creatinine clearance, which was based on a 24-hr urine collection, had only slight depression although early azotemia is evident. A second reversible rejection occurred at 14 days with recurrence of renal failure, weight gain, and temporary depression of white count. Note that steroids completely masked the fever of rejection. The patient has normal renal function in June, 1964, more than 150 days after operation (see Table 1).