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Course of a patient (LD 10) who died of late rejection 295 days after homotransplantation. The donor was unrelated. The diagnosis of rejection was first made at 229 days, but effective adjustments in therapy were not made. Note the transient fall in blood urea nitrogen after local irradiation of the transplant. Vigorous therapy was withheld for too long, and uremia became progressive and irreversible. Terminally, he had multiple pulmonary emboli.
