Table 2.

Vasa Vasorum parameters (normalized to coronary lumen radius) and histological measurements.

	Normal (n=6)	High- Cholesterol (n=6)	High- Cholesterol +Thalidomide (n=6)	Normal + Thalidomide (n=6)
VV Density (n/mm²)	2.7±0.3	6.4±0.7 *,#	3.5±0.8	3.8±0.9
VAF (%)	0.7±0.2	1.6±0.2 §	1.0±0.3	1.2±0.2
ESF (mm²/mm³)	43±5	104±9 §	62±18	64±13
Ratio VV Endothelial Surface/Luminal Endothelial Surface	24±3%	61±7% §	40±12%	41±7%
Intima-Media Thickness (mm)	0.28±0.02	0.62±0.09 †,#	0.35±0.02	0.29±0.03

Data are presented in Mean±SEM.

VAF=vascular area fraction, ESF=endothelial surface fraction

^*p<0.01 vs. Normal

^#p<0.05 vs. High-Cholesterol + Thalidomide

^§p<0.05 vs. Normal

^†p ≤ 0.001 vs. Normal and Normal + Thalidomide

^$p<0.05 vs. all other groups