Table 5.
Within and between group hormonal changes from baseline (T1) through week 8 (T3)
| Variable | Group | Baseline (T1) | Week 4 (T2) | Week 8 (T3) | Between Group |
|---|---|---|---|---|---|
| Estrogen | FEN | 102 ± 67 | 107 ± 55 | 109 ± 60 | G = 0.196 |
| (pg/ml) | PLA | 83 ± 32 | 83 ± 31 | 91 ± 32 | T = 0.173 |
| G × T = 0.563 | |||||
| Cortisol | FEN | 75 ± 23 | 77 ± 27 | 74 ± 28 | G = 0.805 |
| (mg/dl) | PLA | 88 ± 80 | 60 ± 21 | 85 ± 85 | T = 0.418 |
| G × T = 0.324 | |||||
| Insulin | FEN | 15 ± 8 | 13 ± 6 | 15 ± 8 | G = 0.299 |
| (uIU/mL) | PLA | 15 ± 10 | 17 ± 10 | 16 ± 9 | T = 0.962 |
| G × T = 0.060 | |||||
| Leptin | FEN | 15 ± 14 | 13 ± 14 | 19 ± 16 | G = 0.974 |
| (uIU/mL) | PLA | 14 ± 11 | 16 ± 12 | 17 ± 12 | T = 0.044† |
| G × T = 0.351 | |||||
| Free | FEN | 40 ± 33 | 33 ± 22 | 36 ± 22 | G = 0.020† |
| Testosterone | PLA | 57 ± 47 | 66 ± 53† | 67 ± 54† | T = 0.829 |
| (ng/ml) | G × T = 0.318 | ||||
| DHT (pg/ml) | FEN | 1263 ± 496 | 1152 ± 466 | 1144 ± 447 | G = 0.921 |
| PLA | 1187 ± 482 | 1156 ± 448 | 1258 ± 493 | T = 0.134 | |
| G × T = 0.033† |
Abbreviations: FEN = fenugreek supplement group, PLA = placebo group
Symbols: † = Significant between group difference (p < 0.05)