Table 5.
The proportion of early-onset cancer cases by location in the hereditary group in comparison with the whole studied Valka population.
| Location | Hereditary cancers | Valka population | |||
|---|---|---|---|---|---|
| N | Prop. (95% CI) | N | Prop. (95% CI) | p < 0.051 | |
| Colorectal | 19/92 | 20.6 (13.6-30.0) | 43/777 | 5.8 (4.3-7.7) | Yes |
| Endometrial | 51/181 | 28.2 (22.1-35.1) | 158/1094 | 15.1(13.1-17.5) | Yes |
| Breast | 170/310 | 54.8 (49.3-60.3) | 279/1364 | 21.8(19.7-24.2) | Yes |
| Ovarian | 16/51 | 31.4 (20.3-45.0) | 39/156 | 27.1 (20.5-34.9) | No |
| Lung | 35/232 | 15.0 (11.1-20.3) | 147/1795 | 8.3 (7.1-9.6) | Yes |
| Stomach | 20/225 | 8.9 (5.8-13.3) | 162/1615 | 10.2 (8.8-11.8) | No |
| Pancreas | 0/21 | 0 (0-15.5) | 19/302 | 6.3 (4.1-9.6) | No |
| Prostate | 4/37 | 10.8 (4.3-24.7) | 12/499 | 2.6 (1.5-4.4) | No |
| Haematologic | 13/37 | 35.1 (21.8-51.2) | 115/687 | 16.9 (14.3-19.9) | Yes |
| Urinary bladder | 0/24 | 0 (0-13.8) | 11/249 | 4.6 (2.6-8.1) | No |
| Brain | 10/43 | 23.3 (13.1-37.3) | 14/96 | 14.9 (9.1-23.5) | No |
1Difference statistically significant at p < 0.05
N, number of early-onset cases/whole number of reported cases; Prop., proportion.