Table 1.
Clinical EAE course and Gf lesion load
| Mouse | EAE score at Gf imaging | Gf lesion load in mm3 | Day of clinical onset |
|---|---|---|---|
| 1 | 1 | 30.5933 | 10 |
| 2 | 3 | 22.0243 | 9 |
| 3 | 3 | 19.7933 | 11 |
| 4 | 1 | 17.3736 | 13 |
| 5 | 4 | 13.7473 | 6 |
| 6 | 2 | 12.2391 | 7 |
| 7 | 1 | 10.4559 | 9 |
| 8 | 2 | 9.6347 | 9 |
| 9 | 1 | 7.4567 | 9 |
| 10 | 2 | 6.3080 | 9 |
| 11 | 2 | 6.0699 | 9 |
| 12 | 2 | 4.8076 | 11 |
| 13 | 1 | 3.2377 | 11 |
| 14 | 1 | 3.0483 | 11 |
| 15 | 1 | 1.8621 | 11 |
| 16 | 0 | 1.4209 | 11 |
| 17 | 0 | 1.3857 | - |
| 18 | 3 | 0.9528 | 8 |
| 19 | 1 | 0.8987 | 9 |
| 20 | 0 | 0.7135 | - |
| 21 | 0 | 0.5301 | - |
| mean (SD) | 1.48 (+/-1.12) | 8.31 (+/-8.34) | 9.61 (+/-1.69) |
After detection of cranial blood-brain barrier breakdown by Gd-DTPA, 0.1 mmol/kg bodyweight Gf was applied, and MRI repeated after 24 h. The EAE score at the day of Gf imaging and the corresponding lesion volume in T1-weighted Gf-enhanced images are presented. The day of clinical onset is given as days after T cell transfer.