Table 2.
Properties of iMM1415 and comparison with existing models
| iMM1415 | Selvarasu et al (2010). | Evsikov et al (2009). | Quek et al (2008). | Sheikh et al (2005). | |
|---|---|---|---|---|---|
| Dominant reconstruction method | Manual | Manual | Automatic | Automatic | Manual |
| Genes | 1,415 | 724 | 1,060 | 1,399 | 473 |
| Reactions | 3,724 | 715 | 2,018 | 1,757 | 0 |
| Compounds | 2,774 | 1,285 | 1,377 | 2,104 | 872 |
| Compartments | 8 | 3 | 1 | 3 | 3 |
| Reactions | 3,726 | 1,494 | 2,018 | 2,037 | 1,220 |
| Demand& Exchange& Biomass reactions | 455 | 0 | 0 | 0 | 0 |
| Cytosol | 931 | 1,085 | NA | 1,650 | 618 |
| Mitochondrial | 409 | 161 | NA | 387 | 12 |
| Extracellular | 473 | NA | NA | NA | NA |
| Golgi | 250 | NA | NA | NA | NA |
| Lysosome | 194 | NA | NA | NA | NA |
| Ribosome | 184 | NA | NA | NA | NA |
| Peroxisome | 95 | NA | NA | NA | NA |
| Nucleus | 88 | NA | NA | NA | NA |
| Transport | 1,101 | 248 | 0 | 64 | 267 |
| Non-gene associated reactions | 1,514 | 291 | 0 | 148 | 324 |
| Essential genes according to modela | 53a | 109a | NA | NA | 72 |
| Of which experimental data available | 17 | 20 | NA | NA | NA |
| % match to experimental data | 82% | 70% | NA | NA | NA |
| Produces biomass | 1 | 1 | 0 | 1 | 1 |
aunder "minimum growth" medium, differences exist in both biomass and minimum growth medium definitions between publications.
NA - not available