Table 4.
Multivariate-adjusted associations between abdominal adiposity indices and LDL subfractions for white and Japanese men (N=542)
| Predictor variables: abdominal adiposity indices |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| White |
Japanese |
White |
Japanese |
|||||||||
| β (R2) | P | β (R2) | P | β (R2) | P | β (R2) | P | |||||
| Outcome variables: LDL particles |
SAD | WC | Δ (SAD- WC) | SAD | WC | Δ (SAD- WC) | VAT | SAT | Δ (VAT- SAT) | VAT | SAT | Δ (VAT- SAT) |
| Total | ||||||||||||
| Model I | 38.18* (.09) | 7.08† (.05) | 102.52* (.20) | 23.19* (.21) | 2.75* (.10) | .77 (.03) | 6.39* (.23) | 4.99* (.18) | ||||
| Model II | 33.11‡ (.09) | −.91 (.07) | 70.23* (.22) | 19.93† (.21) | 2.41* (.10) | −1.24 (.08) | 4.93* (.24) | 2.79‡ (.19) | ||||
| Model III | 41.41‡ (.09) | −6.10 (.09) | .013 | 57.02† (.23) | 12.73 (.23) | .061 | 2.38† (.11) | −1.20 (.11) | <.001 | 4.60* (.24) | 1.45 (.24) | .104 |
| Intermediate | ||||||||||||
| Model I | 5.27* (.11) | .81† (.05) | 5.56* (.07) | 1.07† (.05) | .30* (.09) | .08 (.03) | .39* (.09) | .21† (.04) | ||||
| Model II | 6.25† (.11) | −.15 (.07) | 6.10† (.07) | 1.68‡ (.06) | .24‡ (.09) | −.18‡ (.09) | .49* (.10) | .18 (.04) | ||||
| Model III | 7.79* (.12) | −1.13 (.12) | <.001 | 5.01‡ (.08) | 1.05 (.08) | .107 | .24‡ (.11) | −.18‡ (.11) | .001 | .48* (.10) | .03 (.10) | .026 |
| Large | ||||||||||||
| Model I | −22.82* (.06) | −3.78‡ (.03) | −39.41* (.11) | −7.81* (.09) | −1.44* (.06) | −.30 (.01) | −2.73* (.15) | −1.38* (.06) | ||||
| Model II | −22.41‡ (.06) | 1.40 (.04) | −39.20* (.11) | −10.37† (.09) | −1.14‡ (.06) | 1.10‡ (.06) | −3.23* (.15) | −.46 (.07) | ||||
| Model III | −29.32‡ (.07) | 5.07 (.07) | .011 | −32.72† (.12) | −6.24 (.12) | .045 | −1.12‡ (.08) | 1.08‡ (.08) | .002 | −3.34* (.15) | .51 (.15) | <.001 |
| Small | ||||||||||||
| Model I | 55.73* (.11) | 10.04 † (.07) | 136.36* (.24) | 29.93* (.23) | 3.89* (.12) | .99‡ (.04) | 8.74* (.29) | 6.16* (.19) | ||||
| Model II | 49.27† (.11) | −2.15 (.09) | 103.30* (.25) | 28.62* (.23) | 3.31† (.13) | −2.15‡ (.11) | 7.67* (.29) | 3.08‡ (.20) | ||||
| Model III | 62.95† (.12) | −10.05 (.12) | .002 | 84.69* (.27) | 17.93‡ (.27) | .012 | 3.25† (.15) | −2.09‡ (.15) | .000 | 7.46* (.29) | .91 (.29) | .003 |
| Size | ||||||||||||
| Model I | −.11* (.12) | −.02* (.07) | −.22* (.23) | −.05* (.20) | −.01* (.13) | −.01‡ (.04) | −.01* (.29) | −.01* (.16) | ||||
| Model II | −.10† (.12) | <.01 (.09) | −.19* (.24) | −.05* (.20) | −.01† (.13) | <.01‡ (.11) | −.01* (.29) | −.01 (.17) | ||||
| Model III | −.12† (.13) | .02 (.13) | .001 | −.16* (.25) | −.03‡ (.25) | .005 | −.01† (.15) | <.01‡ (.15) | <.001 | −.01* (.29) | −.01 (.29) | <.001 |
*
P<0.001,
†
P<0.01,
‡
P<0.05
SAD = sagittal abdominal diameter; WC = waist circumference; VAT = visceral adipose tissue; SAT = subcutaneous adipose tissue For models, the outcome variable is lipoprotein concentration or size; the primary predictor variable is each abdominal adiposity index (SAD, WC, VAT or SAT). Model I: adjusted models for age, pack years of smoking, and alcohol consumption. Model II: adjusted models for further BMI. Model II: BMI-adjusted models when SAD and WC were simultaneously included.