Figure 4.

Examples of fragmented genes that contain frameshift sequencing errors: a gene predicted from a read simulated from the E. coli genome starting at position 4 578 113 (a), and a gene predicted from a metagenomic read from the TS28 dataset (b). The alignments of the nucleotide sequences are partially shown for clarity. The dotted lines connect the regions of nucleotides (with sequencing errors fixed) and the amino acid(s) that they encode. The alignment between the predicted protein from the metagenomic read and its homolog identified in IMG protein database is also shown.