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. Author manuscript; available in PMC: 2010 Nov 11.
Published in final edited form as: Oncogene. 2009 Oct 19;28(50):4434–4443. doi: 10.1038/onc.2009.303

Figure 5.

Figure 5

Retinoblastoma (RB)-deficient mice livers show an increased susceptibility to hepatocellular carcinoma (HCC) when induced by aflatoxin B1 (AFB1). (a) After killing, the livers were excised, weighed and expressed as a percentage of total body weight for both males and females (Rbf/f n = 5, Rbf/f+AFB1 n = 10, Rbf/f albcre+/− n = 8, Rbf/f albcre+/−+AFB1 n = 13 MALES; n = 3 or 5 in each condition for FEMALES). (b) Representative images of excised livers and a table expressing percentages of tumor burden in both female and male livers. (c) Male formalin-fixed, paraffin-embedded (FFPE) liver tissue sections were stained with hematoxylin and eosin (H and E) and representative images were taken to show histology.