Table 1.
Selected studies reporting use of HIFU in the kidney tissues
| Author (Reference) | Country | Animal (A) Human (H) | Outcomes | Extracorporeal (E) or Transcutaneous (T) or Laparoscopic (L) |
|---|---|---|---|---|
| Adams et al.[21] | USA | A | Pathological necrosis in 7/9 lesions | T |
| Hacker et al.[18] | Germany | H-Normal kidney tissue | Pathological changes in 43/43 kidneys | E |
| Illing et al.[25] | United Kingdom | Renal tumors (H) | Necrosis seen in 67% | E |
| Klinger et al.[5] | Austria | Renal tumors (H) | Complete necrosis in 9/10 | L |
| Kohrmann et al.[33] | Germany | Renal tumors (H) | 2/3 showed necrosis on MRI | E[6] |
| Orvieto et al.[34] | USA | A | All 16 lesions in 15 kidneys showed necrosis | L |
| Paterson et al.[35] | USA | A | All lesions showed necrosis | L |
| Roberts et al.[36] | USA | A (normal kidney tissue) | Lesions showed necrosis in all target lesions | T |
| Watkin et al.[37] | United Kingdom | A (normal kidneys) | Lesions seen in target lesions 40% | E |
| Wu et al.[23] | China | Advanced kidney tumors in 10 persons | Complete necrosis in three | E |
| Chapelon et al.[38] | France | A | Necrosis seen in 63% | E |