SNPs associated with AF after adjusting for rs2200733 genotype in the MGH discovery sample were tested for association in the replication samples. The meta-analyzed effects are plotted according to prevalent (odds ratio), incident (hazard ratio), or pooled (relative risk) analysis status. Associations are adjusted for age, sex, and hypertension (MGH, AFNET, ARIC, CHS, RS) or sex only (CCAF). Samples with prevalent AF included MGH, AFNET, CHS, CCAF, and RS. Samples with incident AF included ARIC, CHS, and RS.