TABLE 1.

Neutralization of ΔV1V2 LAI viruses

mAb	WT IC50a	ΔV1V2.2		ΔV1V2.4.DNGSEK		ΔV1V2.9.VK
		IC50a	n-foldb	IC50a	n-Foldb	IC50a	n-Foldb
HIVIg	4.9	0.091	54	0.017	288	0.058	84
CD4-IgG2	0.23	0.0071	32	0.0040	58	0.0050	46
b12	0.57	0.018	32	0.0070	81	0.017	34
b6	13.8	0.049	282	0.036	383	0.045	307
48d	65.0	3.6	18	2.6	25	77.2	0.84
17b	39.4	0.26	152	0.32	123	36.3	1.1
2G12	3.8	0.088	43	0.098	39	0.035	109
447–52D	20.4	0.0015	13600	0.0025	8160	0.0032	6375
2F5	2.2	0.42	5.2	0.12	18	0.66	3.3

^a IC₅₀ values are given in μg/ml.

^b The fold increase in sensitivity compared with WT is given.