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. 2010 Sep 23;285(47):36625–36634. doi: 10.1074/jbc.M110.159954

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — The D1 and D2 receptor are colocalized on presynaptic terminals in rat nucleus accumbens and caudate putamen but are extrasynaptic in the ventral tegmental area. A–C, the D1R and D2R colocalized with SYN but not PSD95 (white circles) in the NAc core, shell, and CP. D, colocalization of D1R and D2R in the neuropil of the VTA was scarce and was not observed with SYN or PSD95 (white circles). In all regions, individual D1R colocalized with SYN or PSD95 (yellow circles). Individual D2R also showed considerable, but diffuse, overlap with SYN or PSD95 (purple color, merge).