TABLE 1.
Effect of the dksA stringent response locus on growth phase levels of pyridine nucleotide pools
Data are from 8–20 observations recorded in at least three independent experiments. ***, p < 0.001 compared with wild-type (WT) bacteria.
| Nucleotide pool | Logarithmic |
Stationary |
||
|---|---|---|---|---|
| WT | dksA | WT | dksA | |
| NADH | 257 ± 68a | 357 ± 92 | 131 ± 24 | 87 ± 15*** |
| NAD+ | 1632 ± 232 | 1532 ± 355 | 731 ± 64 | 1202 ± 161*** |
| NADH/NAD+ | 0.158 | 0.233 | 0.179 | 0.073 |
| NADPH | 1535 ± 149 | 1418 ± 240 | 394 ± 108 | 280 ± 39*** |
| NADP+ | 1391 ± 98 | 1247 ± 173 | 915 ± 141 | 1238 ± 230*** |
| NADPH/NADP+ | 1.103 | 1.137 | 0.431 | 0.227 |
a μm/cell.