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. 2010 Nov 11;6(11):e1000989. doi: 10.1371/journal.pcbi.1000989

Figure 2. Autoregulation and the search of conserved binding sequences.

Figure 2

A) Local regulation at the core of phylogenetic footprinting includes both autoregulation –which can be linked to the regulation of an upstream divergent operon– and downstream unidirectional adjacent regulation (BSs, white boxes). Red and green lines for the respective strict and extended regions of BS search. B–D) Examples of BS logos. Rest of cases in the Appendix of Text S1. Above each logo: the recognition sequence (AA-15, AA-16) and a triad of numbers (i/ii/iii) corresponding to i) the total number of TFs exhibiting the recognition sequence, ii) the number of TFs for which at least a BS was found, and iii) the total number of found BSs. E) Consensus-logo for the BSs associated to the TVSR group. The inserted position NT-2bis for the YQ-logo in C) has not been considered to build the consensus.