Table 2.
All-cause | Breast Cancer | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
N | Deaths | HR1 | 95% CI | HR2 | 95% CI | Deaths | HR1 | 95% CI | HR2 | 95% CI | |
Social Network Size3 | |||||||||||
Small (5–9) | 935 | 133 | 1.00 | 1.00 | 33 | 1.00 | 1.00 | ||||
Small-medium (9) | 854 | 115 | 1.01 | 0.78 to 1.29 | 1.04 | 0.81 to 1.34 | 30 | 0.97 | 0.59 to 1.60 | 1.01 | 0.61 to 1.66 |
Medium (10) | 860 | 84 | 0.76 | 0.58 to 1.01 | 0.88 | 0.67 to 1.17 | 21 | 0.67 | 0.39 to 1.17 | 0.70 | 0.40 to 1.22 |
Medium-large (11–12) | 1,188 | 117 | 0.76 | 0.60 to 0.98 | 0.92 | 0.71 to 1.20 | 39 | 0.93 | 0.59 to 1.49 | 0.97 | 0.59 to 1.58 |
Large (13–16) | 564 | 68 | 0.94 | 0.70 to 1.27 | 1.33 | 0.97 to 1.82 | 19 | 0.98 | 0.56 to 1.73 | 1.07 | 0.59 to 1.96 |
P-trend | 0.08 | 0.55 | 0.80 | 0.98 | |||||||
Number of social ties seen at least once per month4 | |||||||||||
Low (3–5) | 802 | 92 | 1.00 | 1.00 | 22 | 1.00 | 1.00 | ||||
Low-medium (6) | 919 | 130 | 1.30 | 0.99 to 1.70 | 1.24 | 0.95 to 1.62 | 34 | 1.35 | 0.79 to 2.32 | 1.20 | 0.70 to 2.07 |
Medium (7) | 1,022 | 124 | 1.14 | 0.87 to 1.49 | 1.19 | 0.90 to 1.56 | 34 | 1.22 | 0.71 to 2.08 | 1.14 | 0.66 to 1.96 |
Medium-high (8–9) | 1,244 | 130 | 1.01 | 0.77 to 1.32 | 1.10 | 0.83 to 1.44 | 34 | 1.00 | 0.59 to 1.72 | 0.96 | 0.55 to 1.67 |
High (10–13) | 494 | 54 | 0.94 | 0.67 to 1.32 | 1.08 | 0.77 to 1.53 | 18 | 1.37 | 0.73 to 2.56 | 1.33 | 0.70 to 2.55 |
P-trend | 0.29 | 0.89 | 0.87 | 0.86 | |||||||
Overall social connectedness5 | |||||||||||
Low (5–12) | 620 | 93 | 1.00 | 1.00 | 27 | 1.00 | 1.00 | ||||
Low-medium (13–15) | 1,171 | 151 | 0.92 | 0.71 to 1.20 | 1.01 | 0.78 to 1.32 | 35 | 0.68 | 0.41 to 1.12 | 0.69 | 0.41 to 1.14 |
Medium (16–18) | 1,377 | 146 | 0.70 | 0.54 to 0.91 | 0.78 | 0.60 to 1.02 | 33 | 0.55 | 0.33 to 0.92 | 0.58 | 0.34 to 0.97 |
Medium-high (19–20) | 709 | 78 | 0.72 | 0.53 to 0.97 | 0.85 | 0.62 to 1.15 | 25 | 0.83 | 0.48 to 1.43 | 0.94 | 0.54 to 1.65 |
High (21–26) | 467 | 43 | 0.56 | 0.39 to 0.81 | 0.72 | 0.49 to 1.04 | 16 | 0.81 | 0.43 to 1.50 | 0.85 | 0.45 to 1.62 |
P-trend | 0.002 | 0.02 | 0.65 | 0.93 |
Hazard Ratios and 95% Confidence Intervals estimated from models adjusted for age at diagnosis and state of residence.
Hazard Ratios and 95% Confidence Intervals estimated from models adjusted for factors at diagnosis (age, breast cancer stage, state of residence, menopausal status, smoking, hormone replacement therapy use, parity, education), interval between diagnosis and social support assessment, and factors at the time of social support assessment (treatment (radiation, chemotherapy, tamoxifen), physical activity(quintiles), BMI (quintiles), weight change from pre-diagnosis to follow-up).
Ranking of relative network size, including spouse/partner, confidants, children, and close relatives and friends.
Ranking of relative number of children, relatives, and friends seen at least once per month.
Summary score estimating relative frequency of contact with confidants, frequency of attending religious services, frequency of attending community group(s), and number of children, relatives, and friends seen at least once per month.[35]