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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Eur J Pain. 2010 Aug 7;15(3):223–230. doi: 10.1016/j.ejpain.2010.07.003

Figure 2.

Figure 2

Ratings of warmth and heat stimuli. The study subjects received 3 trains of randomly selected 5 sec warm or heat stimuli (35 – 50°C) to either forearm and rated the stimulus intensity using a VAS. All stimuli were delivered by a 3 × 3 cm thermode (Pathway©). After every rating the subjects were asked to indicate whether the stimulus was painful. Whereas the ratings of NC and Family members positively accelerated with increasing stimulus intensity, reaching pain threshold at ≥ 45°C (red symbols), the ratings of the IC did not seem to increase further with heat stimuli of ≥ 44°C. NC=normal control; Family=family except IC; IC=Index Case