TABLE 2.
LRRK2 carriers (n=6) | Control subjects (n=30) | All subjects (n=36) | |
---|---|---|---|
UPDRS-III* | 6.2 ± 6.9 (1-19) | 4.5 ± 6.6 (1-30) | 4.8 ± 6.6 (1-30) |
Trails B speed** | 42.0 ± 8.9 | 31.0 ± 3.1 | 36.0 ± 8.4 |
CDR* | 0.1 ± 0.2 | 0.1 ± 0.2 | 0.1 ± 0.2 |
BIMC* | 0.8 ± 0.7 | 2.3 ± 2.4 | 2.1 ± 2.3 |
FCSRT* (free recall) | 31.8 ± 3.2 | 31.6 ± 5.4 | 31.6 ± 5.1 |
LRRK2: Leucine Rich Repeat Kinase 2; UPDRS-III: Unified Parkinson's Disease Rating Scale, motor subscale, mean±SD (range); CDR: Clinical Dementia Rating Scale, mean±SD; BIMC: Blessed Information Memory Concentration test, mean±SD; FCSRT: Free and Cued Selective Reminding test, mean±SD.
p>0.05;
p=0.02