Table 2.
Summary of Empirical Distributions of Minor-Allele Dosage for True Heterozygotes
| Minor-Allele Count in Reference Haplotypes |
Fraction of Heterozygote Minor-Allele Dosages |
|||
|---|---|---|---|---|
| <0.1 | [0.1, 0.5) | [0.5, 0.9) | ≥ 0.9 | |
| 1 | 0.729 | 0.120 | 0.063 | 0.088 |
| 2 | 0.331 | 0.188 | 0.133 | 0.349 |
| 3 | 0.291 | 0.169 | 0.128 | 0.413 |
| 4 | 0.199 | 0.170 | 0.162 | 0.469 |
| 5 | 0.327 | 0.176 | 0.162 | 0.335 |
| 6 | 0.255 | 0.180 | 0.136 | 0.428 |
| 7 | 0.166 | 0.149 | 0.132 | 0.553 |
| 8 | 0.203 | 0.195 | 0.179 | 0.422 |
| 9 | 0.091 | 0.114 | 0.128 | 0.667 |
| 10 | 0.100 | 0.159 | 0.195 | 0.546 |
| 11–20 | 0.061 | 0.094 | 0.118 | 0.727 |
| 21–30 | 0.043 | 0.054 | 0.092 | 0.811 |
| 31–40 | 0.016 | 0.039 | 0.081 | 0.865 |
| 41–50 | 0.016 | 0.051 | 0.100 | 0.834 |
| 51–60 | 0.006 | 0.023 | 0.050 | 0.921 |
| 61–70 | 0.011 | 0.039 | 0.087 | 0.863 |
| 71–80 | 0.009 | 0.026 | 0.072 | 0.893 |
| 81–90 | 0.007 | 0.017 | 0.054 | 0.923 |
| 91–100 | 0.005 | 0.019 | 0.065 | 0.911 |
Each distribution is conditional on the indicated minor-allele count in the reference haplotypes. Here we report results for sequenced cases and controls.