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A, Effect of cathepsins B and L on microvessel collagen, laminin, and perlecan in normal basal ganglia. B, Effect of E64 (100 µm) on microvessel perlecan degradation by cathepsin B (1.25 U/mL) or cathepsin L (0.2 or 0.8 U/mL). All deficiencies are 2P<0.05 (t test).
