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. 2010 Oct 27;30(43):14560–14572. doi: 10.1523/JNEUROSCI.3247-10.2010

Figure 2.

Figure 2.

Brain-specific loss of dystrolgycan produces a high incidence of hydrocephalus. A–C, Photos of wild-type littermate (upper mouse in each panel) and Nestin-Cre/DG-null (lower mouse in each panel) mice that show the abnormally domed cranium of DG-null mice. D, Gross coronal section of Nestin-Cre/DG-null mouse with severe hydrocephalus. E, Hematoxylin- and eosin-stained coronal section of Nestin-Cre/DG-null mouse. The section roughly corresponds to the gross photo in D. F, Higher-magnification hematoxylin and eosin stain of Nestin-Cre/DG-null cerebral cortex midline. G, Hematoxylin- and eosin-stained section of the aqueduct of Sylvius of a Nestin-Cre/DG-null mouse midbrain. Scale bars, 100 μm.