Table 1. Summary of the HIV RT and Protease Sequence Database Web Site.
Web page |
Description |
URL |
Database documentation | ||
Background; primer | Database rationale for lay audience and novice users | http://hivdb.stanford.edu/hiv/rationale.html |
http://hivdb.stanford.edu/hiv/primer.html | ||
Data model for understanding HIV drug resistance mutations | Description of the sources of knowledge of drug resistance mutations | http://hivdb.stanford.edu/hiv/drm.html |
User guide | Description of database schema and explanation of specific web site features | http://hivdb.stanford.edu/hiv/userguide.html |
Resistance notes | Overview of HIV drug resistance with links to relevant database entries | http://hivdb.stanford.edu/hiv/Notes.pl |
Summary statistics | Dynamically updated summary of database content | http://hivdb.stanford.edu/hiv/summary.pl |
Database query formsa | ||
Mutations | Users retrieve sequences containing a selected mutation or mutations | http://hivdb.stanford.edu/hiv/prmut.pl |
http://hivdb.stanford.edu/hiv/rtmut.pl | ||
Drug therapy | Users retrieve sequences of isolates from patients receiving a selected drug or drug combination. | http://hivdb.stanford.edu/hiv/PI_form.pl |
http://hivdb.stanford.edu/hiv/RTI_form.pl | ||
References | Users retrieve sequences and summaries of data from studies published by the selected author | http://hivdb.stanford.edu/hiv/Reference.pl |
Drug susceptibility | Users retrieve published drug susceptibility data for isolates with selected mutations | http://hivdb.stanford.edu/hiv/Notes.pl |
Sequence analysis programs | ||
HIV-SEQ | Compares new RT and protease sequences to previously published sequences with the same mutations | http://hivdb.stanford.edu/hiv/programs.htm |
Drug resistance interpretation (beta test version) | Infers drug resistance to 15 available drugs using rules hyperlinked to data within the database | http://hiv-4.stanford.edu/hiv/cgi-test/hivtest-web.pl |
aAdditional database query forms include forms providing access to specific amino acid insertions and to nucleotide patterns at specific amino acid positions.