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. Author manuscript; available in PMC: 2010 Nov 12.
Published in final edited form as: J Biol Chem. 2007 Oct 8;282(48):34611–34622. doi: 10.1074/jbc.M707795200

FIGURE 3. Severely reduced growth rate of iPLA2γ KO mice in comparison with WT controls.

FIGURE 3

Total average body weight (g) was measured and plotted versus age (in days) for male (A) and female (B) WT and iPLA2γ KO mice. The results represent 155 measurements of 43 wild type and 33 knock-out males and 25 wild type and 33 knock-out females between the ages of 28 and 282 days. Values represent the mean ± S.E. for each data point. Both male and female iPLA2γ KO animals (dashed lines) had significantly decreased growth (*, p < 0.05) as early as day 28 (by Student’s t test) in comparison with WT littermates (solid lines). KO animals demonstrated severe growth retardation after approximately day 50 with very little weight gain through day 280.