Fig. 2.

KD causes a decrease in insulin-stimulated whole body glucose disposal. A: insulin-stimulated whole body glucose disposal was significantly lower in KD-fed mice (n = 9 per group). This lower level of insulin-stimulated whole body glucose disposal was due to decreased heart muscle glucose uptake (B), as well as decreased brown adipose tissue (BAT) glucose uptake (C); there was no difference in muscle [gastrocnemius (D) and quadriceps (QD, E)] or white adipose tissue (WAT, F) glucose uptake (n = 8 per group). Values are means ± SE. *P < 0.05; **P < 0.01 vs. RC.