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Ion transport affinities in rNCC, flNCC, and mutant clones
| rNCC | TM9 | TM11 | TM12 | flNCC | |
|---|---|---|---|---|---|
| Na+ km, mM | 6.95 ± 1.8 | 9.2 ± 1.5 | 7.7 ± 1.3 | 8.6 ± 1.3 | 31 ± 4.3 |
| Cl− km, mM | 5.25 ± 2.0 | 4.1 ± 1.3 | 4.8 ± 1.0 | 3.3 ± 1.2 | 14 ± 1.3 |
Values are means ± SE. rNCC, rat Na+-Cl− cotransporter; flNCC, flounder Na+-Cl− cotransporter; TM, transmembrane region.
